Magnolia St. Louis, a Tribute Portfolio Hotel, was originally built in 1924 as the Mayfair Hotel by Charles Heiss and shines brightly as the crown jewel of downtown hospitality and sophistication. It is the site of many historical firsts, including the first female general manager in St. Louis and the birthplace of “chocolates on a pillow” by cinematic icon, Cary Grant. Here, each of our 182 guest rooms, including the lavish Cary Grant and Presidential Suites, provide one of downtown St. Louis’s only boutique experiences.